Pyridine, 2-(4-fluorophenyl)-5-methyl-
2-(4-FLUOROPHENYL)-5-METHYLPYRIDINE
CAS: 85237-65-6
Molecular Formula: C12H10FN
Pyridine, 2-(4-fluorophenyl)-5-methyl- - Names and Identifiers
Pyridine, 2-(4-fluorophenyl)-5-methyl- - Physico-chemical Properties
| Molecular Formula | C12H10FN |
| Molar Mass | 187.21 |
| Density | 1.111±0.06 g/cm3(Predicted) |
| Melting Point | 58-59 °C |
| Boling Point | 285.6±25.0 °C(Predicted) |
| pKa | 4.80±0.25(Predicted) |
| Storage Condition | Room Temprature |
Pyridine, 2-(4-fluorophenyl)-5-methyl- - Introduction
2-(4-FLUOROPHENYL)-5-METHYLPYRIDINE is an organic compound with the chemical formula C12H10FN, containing a methyl group and a fluorobenzene group in the structure.
The compound has the form of a white crystal or a solid, and can be dissolved in an organic solvent such as ethanol and dichloromethane. Its melting point is about 72-75 degrees Celsius.
2-(4-FLUOROPHENYL)-5-METHYLPYRIDINE has certain applications in the field of medicine. It can be used as an active intermediate for the synthesis of various compounds, such as biologically active molecules and drugs.
The preparation of 2-(4-FLUOROPHENYL)-5-METHYLPYRIDINE can be obtained by reacting pyrrole with methyl magnesium bromide, and then Nitro reduction reaction with 4-fluoronitrobenzene. The specific steps may be: first, pyrrole is dissolved in anhydrous dichloromethane, then methylmagnesium bromide is added, and after the reaction, it is reacted with 4-fluoronitrobenzene in the presence of a base to obtain the target product.
Regarding safety information, 2-(4-FLUOROPHENYL)-5-METHYLPYRIDINE is an organic compound and should be avoided by inhalation, ingestion and skin contact. During use, it is necessary to wear appropriate protective equipment, such as eye protection and protective gloves. At the same time, make sure to operate under well-ventilated conditions to avoid inhaling harmful gases. When dealing with waste, it should be handled and disposed of in accordance with local regulations.
The compound has the form of a white crystal or a solid, and can be dissolved in an organic solvent such as ethanol and dichloromethane. Its melting point is about 72-75 degrees Celsius.
2-(4-FLUOROPHENYL)-5-METHYLPYRIDINE has certain applications in the field of medicine. It can be used as an active intermediate for the synthesis of various compounds, such as biologically active molecules and drugs.
The preparation of 2-(4-FLUOROPHENYL)-5-METHYLPYRIDINE can be obtained by reacting pyrrole with methyl magnesium bromide, and then Nitro reduction reaction with 4-fluoronitrobenzene. The specific steps may be: first, pyrrole is dissolved in anhydrous dichloromethane, then methylmagnesium bromide is added, and after the reaction, it is reacted with 4-fluoronitrobenzene in the presence of a base to obtain the target product.
Regarding safety information, 2-(4-FLUOROPHENYL)-5-METHYLPYRIDINE is an organic compound and should be avoided by inhalation, ingestion and skin contact. During use, it is necessary to wear appropriate protective equipment, such as eye protection and protective gloves. At the same time, make sure to operate under well-ventilated conditions to avoid inhaling harmful gases. When dealing with waste, it should be handled and disposed of in accordance with local regulations.
Last Update：2024-04-09 21:11:58
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